New insights into nanotherapeutics for periodontitis: a triple concerto of antimicrobial activity, immunomodulation and periodontium regeneration

Abstract Periodontitis is a chronic inflammatory disease caused by the local microbiome and the host immune response, resulting in periodontal structure damage and even tooth loss.Scaling and root planning combined with antibiotics are the conventional means of nonsurgical treatment of periodontitis, but they are insufficient to fully heal periodon

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Risk of myeloid neoplasms after radiotherapy among older women with localized breast cancer: A population-based study.

There are inconsistent and limited data regarding the risk of myeloid neoplasms (MN) among breast cancer survivors who received radiotherapy (RT) in the absence of chemotherapy.Concern about subsequent MN might influence the decision to use adjuvant RT for women with localized disease.As patients with therapy-related MN have generally poor outcomes

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FNAC diagnosis of pleomorphic adenoma of palate

Pleomorphic adenoma also called benign mixed tumor, is the most common salivary gland tumor.Most of these tumors occur Hockey Protective - Elbow Pads - Intermediate in major salivary glands; Parotid gland happens to be the commonly involved one (about 90 %) and about 10 % of these occur in the minor salivary glands.The most common sites for pleomor

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Defective lytic transglycosylase disrupts cell morphogenesis by hindering cell wall de-O-acetylation in Neisseria meningitidis

Lytic Glass Cover Removal Tool transglycosylases (LT) are enzymes involved in peptidoglycan (PG) remodeling.However, their contribution to cell-wall-modifying complexes and their potential as antimicrobial drug targets remains unclear.Here, we determined a high-resolution structure of the LT, an outer membrane lipoprotein from Neisseria species wit

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